Mild Hereditary Spherocytosis--A Family Study

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منابع مشابه

Hereditary spherocytosis-sicklemia in the Negro; case report and study of a Negro family having multiple instances of hereditary spherocytosis.

H EREDITARY SPHEROCYTOSIS in the Negro is a relatively rare occurrence. From a survey of the medical literature of the past 20 years, we have been able to collect 41 cases.1-’4 Some of these cases are subject to doubt as to whether they actually represent hereditary spherocytosis because of insufficient data or the presence of intercurrent disease.”12 It has been suggested by some authors that ...

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Hereditary Spherocytosis Unmasked by Human Parvovirus B19 Induced Aplastic Crisis in a Family

Human parvovirus (HPV) B19 induced aplastic crisis in a family leading to the diagnosis of hereditary spherocytosis (HS) is a very rare condition being barely reported in the literature. We herein report a 4-year-old girl, her brother, and their mother who all presented with progressive pallor and jaundice after a febrile illness. The HPV B19 was diagnosed using polymerase chain reaction (PCR) ...

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Hereditary spherocytosis.

Hereditary spherocytosis is a common inherited disorder that is characterised by anaemia, jaundice, and splenomegaly. It is reported worldwide and is the most common inherited anaemia in individuals of northern European ancestry. Clinical severity is variable with most patients having a well-compensated haemolytic anaemia. Some individuals are asymptomatic, whereas others have severe haemolytic...

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Hereditary spherocytosis.

Hereditary spherocytosis is a congenital haemolytic anaemia due to defect in spectrin-a RBC membrane protein and is transmitted as autosomal dominant. Due to this defect there is presence of characteristic spherical cell in peripheral blood smear and osmotic fragility is increased. Haemolytic anaemia, reticulocytosis, jaundice and splenomegaly are present. This article reports a case of a 9 yea...

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Hereditary Spherocytosis

A 12-year-old girl was brought to the Dhaka Hospital of ICDDR,B with diarrhoea. Incidentally, the parents provided a history of repeated episodes of pallor and jaundice since she was two and half years old. Three of her family members had similar problems. History, clinical examination, and laboratory findings of the girl and her family members suggested a case of hereditary spherocytosis. To o...

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ژورنال

عنوان ژورنال: BMJ

سال: 1960

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5216.1845